A. E. Thalacker-Mercer

This study shows reduced SHMT2 expression or folate availability impairs mitochondrial function, pyruvate kinase activity, and cellular proliferation in cell models.

This study shows that reduced Shmt2 expression and folate deficiency impair mitochondrial dTMP synthesis, increase uracil in mtDNA, and reduce mitochondrial function in mice.

This study shows that NaCT-mediated citrate uptake supports cell survival under nutrient limitation and metal toxicity by enhancing metabolism and lipogenesis.

This study shows that lifelong Ulk1-mediated autophagy deficiency in muscle leads to mitochondrial dysfunction and contractile weakness in aging.

This study identifies serine and glycine as essential for human muscle progenitor cell proliferation and shows their availability declines with age, impairing muscle regeneration.