Allosteric interactions prime androgen receptor dimerization and activation
E. Wasmuth, A. Vanden Broeck, J. R. LaClair, E. A. Hoover, K. E. Lawrence, N. Paknejad, K. J. Pappas, D. Matthies, B. Wang, W. Feng, P. A. Watson, J. C. Zinder, W. Karthaus, M. J. de la Cruz, R. K. Hite, , C. Sawyers
This study identifies allosteric interactions that prime androgen receptor dimerization and activation, revealing structural and functional mechanisms relevant to development and disease.
bioRxiv · Feb 20, 2022Biochemistry