ImmunoStruct: a multimodal neural network framework for immunogenicity prediction from peptide-MHC sequence, structure, and biochemical properties
Kevin Bijan Givechian, João Felipe Rocha, Chen Liu, Edward Yang, Sidharth Tyagi, Kerrie Greene, Rex Ying, Étienne Caron, Akiko Iwasaki, Smita Krishnaswamy
ImmunoStruct improves immunogenicity prediction by integrating peptide-MHC sequence, structure, and biochemical data, showing better performance than existing methods.
Nature Machine Intelligence · Dec 31, 2025Peer-reviewedImmunology