Nuclear NAD+-biosynthetic enzyme NMNAT1 facilitates survival of developing retinal neurons
David Sokolov, Emily Sechrest, Yekai Wang, Connor Nevin, Jianhai Du, Saravanan Kolandaivelu
This study shows that NMNAT1 deletion in developing murine retina causes severe photoreceptor and inner retinal neuron degeneration through multiple cell death pathways and metabolic disruptions.
eLife · Dec 8, 2021Peer-reviewedMolecular Biology