Artificially stimulating retrotransposon activity increases mortality and accelerates a subset of aging phenotypes in Drosophila
Joyce Rigal, Ane Martín Anduaga, Elena Bitman, Emma Rivellese, Sebastián Kadener, Michael T. Marr
This study shows that artificially stimulating retrotransposon activity in Drosophila reduces lifespan and accelerates some aging phenotypes, with dFOXO partially rescuing these effects.
eLife · Aug 18, 2022Peer-reviewedMolecular Biology