Author

Emma Starr

Washington University in St. Louis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Celeste M M. KarchiD· 4 shared Abhirami Kannan IyeriD· 3 shared Guangming HuangiD· 3 shared Jacob A. MarshiD· 3 shared Carlos CruchagaiD· 2 shared Grant Galasso· 2 shared Miguel MinayaiD· 2 shared Rui ZhangiD· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersNeuroscience

Celeste M M. KarchORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

MAPT regulates autophagic-lysosomal function and phagocytosis in human microglia

Kylie J. Schache, Rui Zhang, A. Street, Emma Starr, Jacob A. Marsh, David J.E. Kast, Sally Temple, Abhirami Kannan Iyer, Celeste M M. Karch

This study shows that pathogenic MAPT mutations impair microglial lysosomal and autophagic functions, affecting tau clearance and degradative capacity.

bioRxiv · Sep 1, 2026 · PreprintNeuroscience

The NORAD-pumilio regulatory axis links lncRNA dysregulation to tau propagation-associated phenotypes

Joseph E. Zemke, Guangming Huang, Emma Starr, Matthew Broder, Jacob A. Marsh, Arun Renganathan, Bridget Phillips, Thomas W. Marsh, Miguel Minaya, Carlos Cruchaga, Abhirami Kannan Iyer, Dominantly Inherited Alzheimer Network, Celeste M M. Karch

The paper identifies lncRNA dysregulation in MAPT mutation carriers and shows the NORAD-pumilio axis modulates tau propagation.

bioRxiv · Jul 3, 2026 · PreprintNeuroscience

Integrative Genomic and Functional Analyses Reveal NINL as a Modulator of Tau Aggregation

Samantha K. Swift, Guangming Huang, J. Nicholas Cochran, Ricardo D’Oliveira Albanus, Miguel Minaya, Patricia A. Castruita, Rui Zhang, Katherine J. Miller, Emma Starr, Grant Galasso, Jacob A. Marsh, Aimee W. Kao, Oscar Harari, Jennifer S. Yokoyama, Celeste M M. Karch

The paper identifies NINL as a modulator of tau aggregation through integrative genomic and functional analyses linking it to proteostasis dysfunction in FTD and AD.

Alzheimer s & Dementia · Apr 1, 2026Peer-reviewedNeuroscience

Ms4a4a deficiency ameliorates plaque pathology in a mouse model of amyloid accumulation

Emma Danhash, Anthony C. Verbeck, Daniel Western, Andrea S. Díaz‐Pacheco, Grant Galasso, Shih‐Feng You, Guangming Huang, Emma Starr, Nadia Miller, Collin J. Nadarajah, Savannah J Tiemann, Erik S. Musiek, Jasmin Herz, Abhirami Kannan Iyer, John R. Cirrito, , Celeste M M. Karch

This study shows that Ms4a4a deficiency reduces amyloid beta pathology in mice by enhancing Aβ clearance, supported by increased MMP-9 production in microglia and human CSF data.

Alzheimer s & Dementia · Aug 1, 2025Peer-reviewedNeuroscience