Ms4a4a loss preferentially remodels microglia with limited, compartment-specific effects across central and peripheral immune compartments in 5xFAD mice
Emma Danhash, Anthony C. Verbeck, Abhirami Iyer, Celeste M M. Karch
Author
Washington University in St. Louis
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
3 papers
Recent·Most cited
Emma Danhash, Anthony C. Verbeck, Abhirami Iyer, Celeste M M. Karch
Emma Danhash, Shao‐Yu Fang, Jacob A. Marsh…·Celeste M M. Karch
This study shows that loss of Ms4a4a remodels microglial transcriptional programs and reduces dense-core plaque-associated tau spreading in a mouse model of Alzheimer's disease.
Emma Danhash, Anthony C. Verbeck, Daniel Western…·Celeste M M. Karch
This study shows that Ms4a4a deficiency reduces amyloid beta pathology in mice by enhancing Aβ clearance, supported by increased MMP-9 production in microglia and human CSF data.