Genome-wide transcriptional silencing and mRNA stabilization allow the coordinated expression of the meiotic program in mice
Laura Bellutti, Edith Chan Sock Peng, Victoria Cluzet, Marie-Justine Guerquin, Antoine Rolland, Sébastien Messiaen, Elena Llano, Ihsan Dereli, Emmanuelle Martini, Attila Tóth, Alberto M Pendás, Frederic Chalmel, Gabriel Livera
The paper quantifies transcriptional dynamics in mouse spermatogonia during meiosis, identifying a transcriptional slowdown and mRNA stabilization event that coordinates meiotic gene expression.
bioRxiv · Feb 8, 2024Cell Biology