Attila Tóth

This study identifies ZCWPW1 as a chromatin-based regulator of telomere architecture and meiotic chromosome movements, independent of PRDM9.

This study identifies SYCP2's closure motif as essential for HORMAD2 recruitment to chromosome axes, revealing its role in meiotic synapsis quality control in mice.

The paper quantifies transcriptional dynamics in mouse spermatogonia during meiosis, identifying a transcriptional slowdown and mRNA stabilization event that coordinates meiotic gene expression.

The paper identifies genomic elements and protein interactions that organize meiotic chromosomes for recombination.

The paper identifies IHO1-HORMAD1 as essential for seeding the meiotic DSB machinery on chromosome axes, ensuring sufficient DSBs for homologous chromosome pairing in mice.

This study uses multi-color dSTORM microscopy to analyze RAD51 and DMC1 organization at meiotic DSBs in Hormad1-/- mice, revealing altered recombinase configurations and synaptonemal complex structure.