Author

Eugene Seah

University of Cambridge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 1

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

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Andrian YangiD· 1 shared Bavesh Jawahar· 1 shared Constanza AlcainoiD· 1 shared Dmytro ShepiloviD· 1 shared Fiona Mary GribbleiD· 1 shared Florian T. MerkleiD· 1 shared Frank M. ReimanniD· 1 shared Hsiao‐Jou Cortina CheniD· 1 shared

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1 shared paperNeuroscience

Andrian YangORCID

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1 paper

Recent·Most cited

GLP-1R agonists activate human hypothalamic neurons

Simone Mazzaferro, Hsiao‐Jou Cortina Chen, Olivier Cahn, Andrian Yang, Dmytro Shepilov, Eugene Seah, Jiahui Chen, Bavesh Jawahar, Constanza Alcaino, Viviana Macarelli, Iman D. Mali, John A. Tadross, Fiona Mary Gribble, Frank M. Reimann, John C. Marioni, Florian T. Merkle

This study investigates how GLP-1R agonists affect human hypothalamic neurons derived from pluripotent stem cells, finding they induce depolarization, increased firing, and gene expression changes.

bioRxiv · Apr 2, 2024 · PreprintNeuroscience