The small GTPase Ran defines Nuclear Pore Complex asymmetry
Jenny Sachweh, Mandy Börmel, Sven Klumpe, Anja Becker, Reiya Taniguchi, Marta Anna Kubańska, Verena Pintschovius, Eva Kaindl, Jürgen M. Plitzko, Florian Wilfling, Martin Beck, Bernhard Hampoelz
This study shows that the small GTPase Ran controls the asymmetry of nuclear pore complexes by regulating their peripheral configuration in budding yeast and Drosophila.
Cell · Aug 18, 2025Peer-reviewedCell Biology