Author

Evan T. Hoffman

University of Pennsylvania

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Jeremy B. KatzeniD· 3 shared Aditi MurthyiD· 2 shared Charlotte H Cooper· 2 shared L. Raposo RodrígueziD· 2 shared Willy Roque Barboza· 2 shared Yaniv TomeriD· 2 shared Adam Bennett· 1 shared Ana N. NottinghamiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersMolecular Biology

Jeremy B. KatzenORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Inflammatory Fibroblasts Promote Repair After Injury Through Epithelial Proliferation

L. Raposo Rodríguez, Willy Roque Barboza, Aditi Murthy, Niran Hadad, Sarah Bui, Dakota L Jones, Yaniv Tomer, Charlotte H Cooper, Anamarie Reineberg, Rea Chroneos, Evan T. Hoffman, Surafel Mulugeta, Jeremy B. Katzen, Jonathan A. Kropski, Nicholas E. Banovich, Michael Francis Beers

The paper identifies inflammatory fibroblasts that promote lung repair by enhancing epithelial proliferation through BMP signaling, validated across multiple models and human disease.

bioRxiv · Aug 4, 2026 · PreprintMolecular Biology

Enabling non-viral DNA delivery using lipid nanoparticles co-loaded with endogenous anti-inflammatory lipids

Manthan N. Patel, Sachchidanand Tiwari, Yufei Wang, Sarah O’Neill, Jichuan Wu, Serena Omo‐Lamai, Carolann L. Espy, Liam S. Chase, Aparajeeta Majumder, Evan T. Hoffman, Anit Shah, András Sárközy, Jeremy B. Katzen, Norbert Pardi, Jacob Samuel Brenner

This study develops lipid nanoparticles co-loaded with anti-inflammatory lipids to reduce inflammation from DNA delivery, enabling prolonged transgene expression.

Nature Biotechnology · Feb 5, 2025Peer-reviewedBioengineering

Aberrant Transitional Alveolar Epithelial Cells Promote Pathogenic Activation of Lung Fibroblasts in Preclinical Fibrosis Modeling

Evan T. Hoffman, Willy Roque Barboza, Luis R Rodriguez, Rachna Dherwani, Yaniv Tomer, Aditi Murthy, Adam Bennett, Ana N. Nottingham, Apoorva Babu, Katrina Chavez, Charlotte H Cooper, Maria Ciocca Basil, Micha Sam Brickman Raredon, Jeremy B. Katzen

This study identifies aberrant transitional alveolar epithelial cells in a mouse fibrosis model and shows they activate fibroblasts through a profibrotic secretome.

bioRxiv · Jun 17, 2024 · PreprintCell Biology