Serena Omo‐Lamai

This paper identifies that lipid nanoparticle-induced inflammation arises from endosomal membrane damage and proposes strategies to mitigate it through galectin inhibition or ESCRT-recruiting lipids.

This study develops lipid nanoparticles co-loaded with anti-inflammatory lipids to reduce inflammation from DNA delivery, enabling prolonged transgene expression.

The paper shows that lung marginated neutrophils effectively uptake endothelial-targeted nanoparticles, suggesting they are part of the reticuloendothelial system.

This paper combines affinity moiety targeting and physicochemical tropism in lipid nanoparticles to enhance organ targeting, showing improved specificity and uptake in lungs and brain.