Repeated out-of-Africa expansions of Helicobacter pylori driven by replacement of deleterious mutations
H. A. Thorpe, E. Tourrette, K. Yahara, F. F. Vale, S. Liu, M. Oleastro, T. Alarcon, T. Perets, S. Latifi-Navid, Y. Yamaoka, B. Martinez-Gonzalez, I. Karayiannis, T. Karamitros, D. Sgouras, W. Elamin, , D. Falush
This study shows H. pylori has spread repeatedly from Africa by replacing strains with deleterious mutations through migration and selection.
bioRxiv · Jun 5, 2021Evolutionary Biology