Scalable intracellular delivery via microfluidic vortex shedding enhances the function of chimeric antigen receptor T-cells
B. J. Sytsma, V. Allain, S. Bourke, F. Faizee, M. Fathi, R. Berdeaux, L. M. R. Ferreira, J. W. Brewer, L. Li, F. L. Pan, A. G. Rothrock, W. A. Nyberg, Z. Li, L. H. Wilson, J. Eyquem, R. S. Pawell
This study introduces hydroporation as a scalable and efficient method for delivering CAR-T cells, achieving higher yields and viability compared to traditional methods.
bioRxiv · Jun 25, 2024Bioengineering