Author

F. Holstein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. Muenster-Kuehnel· 1 shared A. Obenauf· 1 shared A. Talebi· 1 shared A.-C. Koenig· 1 shared A.-K. Jochum· 1 shared C. H. Scheel· 1 shared C. von Toerne· 1 shared D. Hoffmann· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Muenster-Kuehnel

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Tumor sialylation controls effective anti-cancer immunity in breast cancer

S. Mereiter, G. Jonsson, T. Oliveira, J. Helm, D. Hoffmann, M. Abeln, A.-K. Jochum, W. Jochum, M. J. Kellner, M. Feith, V. Tkalec, K. Wasilewska, J. Jiao, L. Emsenhuber, F. Holstein, , J. M. Penninger

This study shows that tumor sialylation suppresses anti-cancer immunity in breast cancer by altering immune cell interactions and checkpoint ligands, and that inhibiting sialylation enhances immune response and therapy effectiveness.

bioRxiv · Sep 20, 2023 · PreprintCancer Biology

Cell density-dependent ferroptosis in breast cancer is induced by accumulation of polyunsaturated fatty acid-enriched triacylglycerides

E. Panzilius, F. Holstein, J. Dehairs, M. Planque, C. von Toerne, A.-C. Koenig, S. Doll, M. Bannier-Helaouët, H. M. Ganz, S. M. Hauck, A. Talebi, J. V. Swinnen, S.-M. Fendt, J. P. Friedmann Angeli, M. Conrad, C. H. Scheel

This study shows that low cell density in breast cancer cells increases ferroptosis sensitivity by promoting PUFA-enriched TAG accumulation and reducing lipid desaturation.

bioRxiv · Oct 1, 2019 · PreprintCancer Biology