High-quality SNPs from genic regions highlight introgression patterns among European white oaks (Quercus petraea and Q. robur).
T. Lang, P. Abadie, V. Leger, T. Decourcelle, J.-M. Frigerio, C. Burban, C. Bodenes, E. Guichoux, G. Le Provost, C. Robin, N. Tani, P. Leger, C. Lepoittevin, V. A. El Mujtar, F. Hubert, , P. Garnier-Gere
This study challenges the 'allosteric switch' model of SHP2 activation by showing that the N-SH2 binding cleft is constitutively open in solution and its opening does not drive activation.
bioRxiv · Jan 15, 2021 · PreprintEvolutionary Biology