Author

N. Dusetti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 5

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 4 Approach:experimental assay· 4 Organism:human· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:imaging· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

L. Buscail· 2 shared P. Cordelier· 2 shared A. Bardier-Dupas· 1 shared A. El kaoutari· 1 shared A. Etzerodt· 1 shared A. Frances· 1 shared A. Kamoun· 1 shared A. Lemarie· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersCancer Biology

L. Buscail

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

EZH2 deletion does not impact acinar cell regeneration but restricts progression to pancreatic cancer in mice

E. Jaune-Pons, X. Wang, F. Mousavi, A. El kaoutari, K. Berger, C. Johnson, M. Martin, S. Aggarwal, S. Brar, K. Muhammad, P. Shooshtari, A. Mathison, N. Dusetti, R. Urrutia, G. Lomberk, C. L. Pin

This study shows EZH2 deletion in adult acinar cells does not block regeneration but limits PDAC progression by altering the tumor microenvironment and differentiation.

bioRxiv · Sep 25, 2023 · PreprintCancer Biology

Minute virus of mice is oncolytic for pancreatic cancer cells with mesenchymal phenotype

P. Garcin, H. Lulka, M. Vienne, N. Dusetti, L. Buscail, P. Cordelier

This study shows that the minute virus of mice (MVMp) selectively targets and kills mesenchymal, basal-like pancreatic cancer cells, both in vitro and in vivo, offering a potential precision therapy for aggressive pancreatic tumors.

bioRxiv · Apr 11, 2023 · PreprintCancer Biology

Cytidine deaminase regulates mitochondrial biogenesis in pancreatic cancer cells

A. Frances, A. Lumeau, L. Stuani, M. Gayral, E. Salland, N. Bery, D. Pagan, N. Hanoun, J. Torrisani, A. Lemarie, J.-C. Portais, L. Buscail, N. Dusetti, J.-E. Sarry, P. Cordelier

This study shows that Cytidine deaminase (CDA) promotes mitochondrial biogenesis and oxidative phosphorylation in pancreatic cancer cells, independent of its deaminase activity, revealing new therapeutic targets.

bioRxiv · Dec 15, 2022 · PreprintCancer Biology

PACpAInt: a deep learning approach to identify molecular subtypes of pancreatic adenocarcinoma on histology slides

C. Saillard, F. Delecourt, B. Schmauch, O. Moindrot, M. Svrcek, A. Bardier-Dupas, J.-F. Emile, M. Ayadi, V. Rebours, L. de Mestier, P. Hammel, C. Neuzillet, J.-B. Bachet, J. Iovanna, N. Dusetti, , J. Cros

PACpAInt uses deep learning to identify molecular subtypes of pancreatic adenocarcinoma on histology slides, revealing prognostic heterogeneity and novel subtypes.

bioRxiv · Jan 4, 2022 · PreprintCancer Biology

Sympathetic axonal sprouting induces changes in macrophage populations and protects against pancreatic cancer

J. Guillot, C. Dominici, A. Lucchesi, T. T. H. Nguyen, J. Nigri, F. Guillaumond, M. Bigonnet, N. Dusetti, A. Etzerodt, T. Lawrence, P. Pudlo, F. Hubert, J.-Y. Scoazec, S. A. van de Pavert, R. Tomasini, , F. Mann

This study shows that sympathetic axonal sprouting alters macrophage populations and reduces pancreatic cancer progression.

bioRxiv · Apr 27, 2020Cancer Biology