Genotypic identification of polyclonal plasma cells in plasma cell dyscrasias shows an aberrant single-cell phenotype with clinical implications
M. C. Da Via, F. Lazzaroni, A. Matera, A. Marella, A. Maeda, C. De Magistris, L. Pettine, S. Fabris, S. Pioggia, A. Marchetti, M. Barbieri, S. Lonati, A. Cattaneo, M. Tornese, M. Scopetti, , N. Bolli
The paper identifies polyclonal plasma cells in plasma cell dyscrasias using single-cell RNAseq and shows their pro-inflammatory status and clinical relevance through a derived signature.
bioRxiv · May 26, 2024 · PreprintCancer Biology