Author

A. Maeda

Brigham and Women's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Assay:scRNA-seq· 3 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

M. Takahashi· 2 shared N. Sakai· 2 shared A. Cattaneo· 1 shared A. Hasegawa· 1 shared A. Marchetti· 1 shared A. Marella· 1 shared A. Matera· 1 shared A. Neri· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersCell Biology

M. Takahashi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

MDA5 multimerization on LINE RNA drives pathogenic extracellular immune complexes in autoimmunity

T. Hsu, Xi Wang, Jiayan Zhang, Yukari Isayama, Viktoria E. M. Schindler, Eveline Van Gompel, Hadil Maadadi, Celia Torres-Arancivia, Akiko Shimazaki-Takahashi, Nina Kurihara, Mariko Kondo, Marina Galesic, Antonella Notarnicola, Sharmin Sultana, A. Maeda, , Sun Hur

Patient-derived anti-MDA5 antibodies bind MDA5 filaments in two germline-encoded modes; only filament immune complexes activate innate immunity, with LINE-derived dsRNA scaffolding circulating filaments in patient plasma.

bioRxiv · Jul 31, 2026 · PreprintBiochemistry✦ In-depth digest

Genotypic identification of polyclonal plasma cells in plasma cell dyscrasias shows an aberrant single-cell phenotype with clinical implications

M. C. Da Via, F. Lazzaroni, A. Matera, A. Marella, A. Maeda, C. De Magistris, L. Pettine, S. Fabris, S. Pioggia, A. Marchetti, M. Barbieri, S. Lonati, A. Cattaneo, M. Tornese, M. Scopetti, , N. Bolli

The paper identifies polyclonal plasma cells in plasma cell dyscrasias using single-cell RNAseq and shows their pro-inflammatory status and clinical relevance through a derived signature.

bioRxiv · May 26, 2024 · PreprintCancer Biology

Pigmentation level of human iPSC-derived retinal pigment epithelium cell does not indicate a specific gene expression profile

Y. Nakai-Futatsugi, J. Jin, T. Ogawa, N. Sakai, A. Maeda, K.-i. Hironaka, M. Fukuda, H. Danno, Y. Tanaka, S. Hori, K. Shiroguchi, M. Takahashi

The paper analyzes the relationship between pigmentation level and gene expression in human iPSC-derived RPE cells, finding no specific gene expression profile correlates with color intensity.

bioRxiv · Sep 29, 2023 · PreprintCell Biology

Inducing Human Retinal Pigment Epithelium-like Cells from Somatic Tissue

I. N. Woogeng, I. Abugessaisa, A. Tachibana, Y. Sahara, C.-C. Hon, A. Hasegawa, B. Kaczkowski, N. Sakai, M. Nishida, H. Hu, H. Sanyal, J. Sho, T. Kasukawa, M. Takasato, P. Carninci, , C. Kime

This study develops a simplified method to induce RPE-like cells from human fibroblasts and validates their properties using single-cell RNA sequencing.

bioRxiv · Jul 27, 2020Bioengineering