Metamorphic proteins at the basis of human autophagy initiation and lipid transfer
A. Nguyen, F. Lugarini, C. David, P. Hosnani, B. Knotkova, A. Patel, I. Parfentev, A. Friedrich, H. Urlaub, M. Meinecke, B. Stork, A. Faesen
This study identifies the molecular mechanism of autophagy initiation by revealing the role of metamorphic proteins ATG13-101 in forming the autophagy initiation supercomplex.
bioRxiv · Sep 21, 2022Biochemistry