PD-1 Specific 'Blocking' Antibodies That Deplete PD-1+ T Cells Present An Inconvenient Variable In Pre-clinical Immunotherapy Experiments
F. Polesso, M. W. Munks, K. H. Rott, S. Smart, A. B. Hill, A. E. Moran
This study shows that some anti-PD-1 antibodies in mice can deplete PD-1+ T cells, affecting experimental outcomes in immunotherapy studies.
bioRxiv · Apr 14, 2020Immunology