S. Smart

Metabolic clearance rate modeling: A translational approach to quantifying cerebral metabolism using hyperpolarized pyruvate.

This paper introduces a model-free method to quantify cerebral metabolism using hyperpolarized pyruvate MRI and demonstrates its application in pre-clinical stroke and healthy human brain studies.

CD8 T Cell Memory Inflation is Driven by Latent CMV Infection of Lymphatic Endothelial Cells

The paper identifies lymphatic endothelial cells as the source of antigen presentation driving CD8 T cell memory inflation during latent CMV infection.

PD-1 Specific 'Blocking' Antibodies That Deplete PD-1+ T Cells Present An Inconvenient Variable In Pre-clinical Immunotherapy Experiments

This study shows that some anti-PD-1 antibodies in mice can deplete PD-1+ T cells, affecting experimental outcomes in immunotherapy studies.

Drivers of vascular plant species area relationships in British broadleaved woodlands and their effects on the species area curve

This paper investigates drivers of vascular plant species area relationships in British woodlands, finding that habitat heterogeneity and proximity to natural habitats increase species richness, while soil organic matter and succession decrease it.

Magnetic resonance imaging of the regenerating neonatal mouse heart

This study uses MRI to track neonatal mouse heart regeneration after coronary artery ligation, showing regenerative responses in P1 animals versus fibrotic responses in P7 animals.