Cross-protective immune responses induced by sequential influenza virus infection and by sequential vaccination with inactivated influenza vaccines
W. Dong, Y. Bhide, F. Sicca, T. Meijerhof, K. Guilfoyle, O. G. Engelhardt, L. Boon, C. A.M. de Haan, G. Carnell, N. Temperton, J. de Vries-Idema, D. J. Kelvin, A. Huckriede
This study shows that sequential vaccination with inactivated influenza vaccines can reduce pandemic virus infection severity, while subunit vaccines cannot, through cross-reactive antibodies and CD8+ T cells.
bioRxiv · May 31, 2018Microbiology