F. Souaze

Cancer associated fibroblasts mitigate the efficacy of the combination treatment of chemotherapy and BCL-xL targeting in triple negative breast cancer cells

This study shows that BCL-xL promotes chemotherapy resistance in TNBC cells, and CAFs reduce the effectiveness of chemotherapy combined with BCL-xL inhibition.

SARS-CoV-2 E and 3a proteins are inducers of pannexin currents

This paper investigates whether SARS-CoV-2 E and 3a proteins act as viroporins and finds they instead induce cell shape changes and death, indirectly activating pannexin channels.

Targeting of MCL-1 in breast cancer associated fibroblasts reverses their myofibroblastic phenotype and pro-invasive properties

This study shows that targeting MCL-1 in breast cancer-associated fibroblasts reduces their myofibroblastic traits and pro-invasive properties.