Cell BiologybioRxiv
SARS-CoV-2 E and 3a proteins are inducers of pannexin currents
B. Oliveira Mendes, M. Alameh, B. Ollivier…·G. Loussouarn
This paper investigates whether SARS-CoV-2 E and 3a proteins act as viroporins and finds they instead induce cell shape changes and death, indirectly activating pannexin channels.
DOI 10.3390/cells12111474