A Mimicry-Based Strategy Between Human and Commensal Antigens for the Development of a New Family of Immune Therapies for Cancer
A. Talpin, A. Maia, J.-M. Carpier, G. Kulakowski, C. Gaal, F. Strozzi, C. Billerey, L. Aubergeon, L. Amable, J. Kervevan, T. Mersceman, A. Garnier, C. P. Oliveira, C. Calderon, D. Bachrouche, , J. Gamelas Magalhaes
This paper introduces OncoMimics, a peptide-based immunotherapy using molecular mimicry between commensal bacterial and tumor antigens to induce cross-reactive T cell responses, showing early clinical success in glioblastoma.
bioRxiv · May 27, 2024Immunology