Testing of the survivin suppressant YM155 in a large panel of drug-resistant neuroblastoma cell lines
M. Michaelis, Y. Voges, F. Rothweiler, F. Weipert, A. Zhia-Amad, J. Cinatl, A. von Deimling, F. Westermann, F. Roedel, M. N. Wass, J. Cinatl
This study tests YM155 in 101 neuroblastoma cell lines, revealing ABCB1 and ABCC1 as mediators of resistance and highlighting cross-resistance differences between drug-adapted lines.
bioRxiv · Jan 27, 2020Pharmacology & Toxicology