Author

F.-Y. Su

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 4

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Assay:multiome· 1

Frequent Co-Authors

G. A. Kwong· 4 shared H. Phuengkham· 3 shared S. N. Dahotre· 3 shared A. M. Harris· 2 shared A. Sivakumar· 2 shared L. Gamboa· 2 shared A. D. Silva Trenkle· 1 shared A. H. Zamat· 1 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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4 shared papersBioengineering

G. A. Kwong

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Sensitizing solid tumors to CAR-mediated cytotoxicity using synthetic antigens

L. Gamboa, A. H. Zamat, D. Vanover, C. A. Thiveaud, H. E. Peck, H. Phuengkham, A. Sivakumar, A. M. Harris, S. N. Dahotre, F.-Y. Su, P. J. Santangelo, G. A. Kwong

This study develops synthetic antigens to enhance CAR T cell efficacy against solid tumors by reducing off-target effects and improving tumor targeting.

bioRxiv · Dec 11, 2021 · PreprintBioengineering

In vivo mRNA delivery to virus-specific T cells by light-induced ligand exchange of MHC class I antigen-presenting nanoparticles

F.-Y. Su, Q. Zhao, S. N. Dahotre, L. Gamboa, S. S. Bawage, A. D. Silva Trenkle, A. Zamat, H. Phuengkham, R. Ahmed, P. Santangelo, G. A. Kwong

The paper develops a method to deliver mRNA to multiple virus-specific T cells using light-induced ligand exchange of MHC class I antigen-presenting nanoparticles, achieving ~50% transfection in vivo.

bioRxiv · Oct 14, 2021Bioengineering

Synthetic Antigen-Presenting Cells for Adoptive T Cell Therapy

S. N. Dahotre, A. M. Romanov, F.-Y. Su, G. A. Kwong

This paper develops synthetic antigen-presenting cells (APCs) that activate T cells effectively without conventional APCs, showing improved tumor control in mice.

bioRxiv · Feb 1, 2021Bioengineering

Activity-based urinary biomarkers of response and resistance to checkpoint blockade immunotherapy

Q. D. Mac, C. Xu, J. R. Bowen, A. Sivakumar, H. Phuengkham, F.-Y. Su, S. Z. Stentz, H. Sim, A. M. Harris, T. T. Li, P. Qiu, G. A. Kwong

This paper develops INSIGHT, a mass-barcoded peptide sensor for noninvasive monitoring of checkpoint blockade therapy response and resistance in mice.

bioRxiv · Dec 10, 2020 · PreprintBioengineering