B cell receptor crosslinking can augment T cell help-mediated germinal center B cell selection.
Jackson S. Turner, Fang Ke, Irina L. Grigorova
This study shows that T cell help alone can drive GC B cell expansion and plasmablast formation, while BCR crosslinking synergizes with T cell help to enhance these responses when T cell help is limited.
bioRxiv · Aug 29, 2018 · PreprintImmunology