Fei Yang

Extracellular Granzyme B Promotes Melanocytorrhagy, Melanocyte Senescence and Aberrant Epidermal Differentiation in Vitiligo and Is Therapeutically Targetable

This study shows extracellular Granzyme B contributes to vitiligo by causing melanocyte detachment, senescence, and abnormal epidermal differentiation, and identifies it as a therapeutic target.

dbGIST: An LLM-Assisted Multi-Omics Resource for Target Exploration and Cross-Dataset Validation in Gastrointestinal Stromal Tumors

dbGIST is a multi-omics resource for GIST research that integrates diverse datasets and provides analytical tools for target exploration and cross-dataset validation.

Aberrant laminin signaling drives melanocyte dedifferentiation and unveils a tractable therapeutic target in vitiligo

This study identifies melanocyte dedifferentiation as a reversible mechanism in vitiligo and shows that targeting specific pathways can restore pigmentation.

Methyl gallate Attenuates Post-Stroke Emotional and Cognitive Symptoms by Promoting Hippocampal Neurogenesis via PI3K/GSK3 and AMPK Signaling

This study shows that methyl gallate improves post-stroke depression and cognitive impairments by enhancing hippocampal neurogenesis through PI3K/GSK3 and AMPK signaling.

Prickle and Ror modulate Dishevelled-Vangl interaction to regulate non-canonical Wnt signaling during convergent extension