Author

Feng Chen

Nanchang University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Biochemistry· 1 Bioinformatics· 1 Genetic & Genomic Medicine· 1 Genomics· 1 Pharmacology & Toxicology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 4 Approach:statistical model· 4 Research Focus:differential expression· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Approach:Bayesian inference· 1

Frequent Co-Authors

Alex Hastie· 1 shared Alexander W Zaranek· 1 shared Ali BashiriD· 1 shared Ali Moshrefi· 1 shared Arend SidowiD· 1 shared Brittany A. GoodsiD· 1 shared Chenze Ren· 1 shared Chris Mason· 1 shared

Activity by Year

2014-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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1 shared paperGenomics

Alex Hastie

Mutual co-authors in cluster

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6 papers

Recent·Most cited

Single-cell transcriptome-wide Mendelian randomization and colocalization analyses reveal immune-cell-specific mechanisms and actionable drug targets in prostate cancer

Yanggang Hong, Yi Wang, Yirong Wang, Feng Chen, Jiajun Li

The paper identifies immune-cell-specific genetic associations and drug targets in prostate cancer using integrative analyses of single-cell and bulk data.

medRxiv · Oct 28, 2026 · PreprintGenetic & Genomic Medicine

PASTRI: Resolving Stage-Specific Cell-State Dynamics from Annotated Cell Lineage Trees

Wenjing Yang, Zizhang Li, Xiaochen Yu, Peng Wu, Xiaoyu Zhang, Chenze Ren, Kehui Liu, Jingyu Chen, Feng Chen, Xionglei He, Jiajun Zhang, Xiaoshu Chen, Jianrong Yang

PASTRI infers stage-specific cell-state transition rates from annotated cell lineages, revealing rate-limiting steps and attractor states in development and disease.

bioRxiv · Aug 20, 2026 · PreprintBioinformatics

A Designed Ankyrin Repeat Protein (DARPin) Targeting EGFR Inhibits Ovulation and Enables a Novel Platform for Studying Ovarian Biology and Pathophysiology

Yubing Liu, Jiyang Zhang, Shichao Liu, Connie Mitra, Yue Liu, Hannah M. VanBenschoten, Brittany A. Goods, Feng Chen, Shuo Xiao

An engineered EGFR-targeting DARPin selectively inhibits ovulation through extracellular receptor blockade and establishes a versatile platform for investigating ovarian signaling and reproductive disorders.

bioRxiv · Jun 26, 2026 · PreprintPharmacology & Toxicology

Discovery and characterization of a lactonase in gut microbiota that initiates the metabolism of ellagic acid

Zhike Xie, Jiaxin You, Feifei Xin, Feng Chen, Qiangqiang Ma, Yiping Guo, Zheng Ruan

This study identifies and characterizes an EA lactonase from gut bacteria that metabolizes ellagic acid into urolithin, revealing its structure and biochemical mechanism.

bioRxiv · Dec 7, 2025 · PreprintBiochemistry

Extensive sequencing of seven human genomes to characterize benchmark reference materials

Justin M Zook, David Catoe, Jennifer McDaniel, Lindsay Vang, Noah Spies, Arend Sidow, Ziming Weng, Yuling Liu, Chris Mason, Noah Alexander, Dhruva Chandramohan, Elizabeth Henaff, Feng Chen, Erich Jaeger, Ali Moshrefi, , Sofia K

The paper presents extensive sequencing data from seven human genomes to serve as benchmark reference materials for improving sequencing technologies and variant calling.

bioRxiv · Dec 23, 2015Genomics

Different profile of transcriptome between wheat Yunong 201 and its high-yield mutant Yunong 3114

Feng Chen, Zhongdong Dong, Zhang Ning, Zhang Xiangfen, Dangqun Cui

The paper compares the transcriptome of wheat Yunong 201 and its high-yield mutant Yunong 3114 to identify molecular mechanisms underlying increased yield.

bioRxiv · May 27, 2014 · PreprintPlant Biology