Author

Fengli Guo

Stowers Institute for Medical Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Developmental Biology· 5

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Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Organism:non-human primate· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Paul A. TrainoriD· 3 shared Chris W. SeideliD· 2 shared Mary Cathleen McKinneyiD· 2 shared MaryEllen Kirkman· 2 shared Xia ZhaoiD· 2 shared Alejandro Sánchez AlvaradoiD· 1 shared Andrew J. PriceiD· 1 shared Anna M. L. KlompeniD· 1 shared

Activity by Year

2015-2026 · peak 2/yr

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10 top collaborators · 20 mutual co-author links

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3 shared papersDevelopmental Biology

Paul A. TrainorORCID

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6 papers

Recent·Most cited

Loss of polr1c disrupts myelination in a zebrafish model of POLR1C-associated disease

Lauren B. Sands, Camille E. A. Goo, Laura K. White, Bailey T. Lubash, Mary Cathleen McKinney, Fengli Guo, Chris W. Seidel, Xia Zhao, Paul A. Trainor, Kristin E. Noack Watt

This study shows that loss of polr1c in zebrafish causes reduced myelination and craniofacial defects, with Tp53 pathway activation but no apoptosis in oligodendrocyte precursors.

bioRxiv · Sep 25, 2026 · PreprintDevelopmental Biology

Graded FGF activity patterns distinct cell types within the apical sensory organ of the sea anemone Nematostella vectensis

Keith Z. Sabin, Shiyuan Chen, Eric M. Hill, Kyle J. Weaver, Jacob Yonker, MaryEllen Kirkman, Bret Redwine, Anna M. L. Klompen, Xia Zhao, Fengli Guo, Cathy McKinney, Jessica L. Dewey, Matthew C. Gibson

The paper identifies two cell types in the sea anemone's apical sensory organ and shows FGF signaling regulates their development through a gene regulatory network.

bioRxiv · Jun 7, 2023 · PreprintDevelopmental Biology

Morphological changes and two Nodal paralogs drive left-right asymmetry in the squamate veiled chameleon (C. calyptratus).

Natalia A. Shylo, Sarah E. Smith, Andrew J. Price, Fengli Guo, Melainia L. McClain, Paul A. Trainor

This study shows veiled chameleon embryos lack motile cilia in the L-R organizer and express two Nodal paralogs, revealing a novel mechanism for left-right asymmetry evolution.

Frontiers in Cell and Developmental Biology · Apr 11, 2023Peer-reviewedDevelopmental Biology

rRNA transcription is integral to liquid-liquid phase separation and maintenance of nucleolar structure

Soma Dash, Maureen C. Lamb, Jeffrey J. Lange, Mary Cathleen McKinney, Dai Tsuchiya, Fengli Guo, Xia Zhao, Timothy J. Corbin, MaryEllen Kirkman, Kym M. Delventhal, Emma L. Moore, Sean McKinney, Rita Shiang, Paul A. Trainor

The paper shows that rRNA transcription by Pol I is essential for nucleolar structure and liquid-liquid phase separation in mouse embryos.

bioRxiv · Nov 14, 2022 · PreprintDevelopmental Biology

Cellular, ultrastructural and molecular analyses of epidermal cell development in the planarian Schmidtea mediterranea

Li-Chun Cheng, Kimberly C. Tu, Chris W. Seidel, Sofia M. C. Robb, Fengli Guo, Alejandro Sánchez Alvarado

The paper identifies transcriptional regulators of epidermal lineage differentiation in planarians and discovers novel secreted organelles.

Developmental Biology · Oct 31, 2017Peer-reviewedDevelopmental Biology

Crucial Roles of the Arp2/3 Complex during Mammalian Corticogenesis

Pei-Shan Wang, Fu-Sheng Chou, Fengli Guo, Praveen Suraneni, Sheng Xia, Sree Ramachandran, Rong Li

This study shows that the Arp2/3 complex is essential for radial glial cell polarity, morphogenesis, and neuronal migration during cortical development.

bioRxiv · Sep 6, 2015