Transcriptomic and functional comparison of cells isolated from healthy and degenerated ovine intervertebral discs
Paul Humbert, Lucie Danet, Emmaëlle Carrot, Floriane Etienne, Boris Halgand, Frédéric Blanchard, Claire S. Vinatier, Jérôme Guicheux, Marion Fusellier, Catherine Le Visage, Romain Guiho
This paper compares transcriptomic and functional differences between healthy and degenerated ovine intervertebral disc cells, finding age-related inflammatory and senescence signatures and shared transcriptional modules with human degenerated discs.
Journal of Cellular and Molecular Medicine · Jan 1, 2026Peer-reviewedCell Biology