ERα mediated gene state switching regulates the extent of the single-cell estrogen response
C. R. Day, P. Yasar, G. Adedoyin, B. Bennett, J. Rodriguez
The paper investigates how altered ERα function and cofactor recruitment affect transcriptional bursting in estrogen responsive genes, finding gene-specific reductions in active alleles in BPA-treated cells.
bioRxiv · Oct 18, 2023 · PreprintCell Biology