Human Gastric Multi-Regional Assembloids Favour Functional Parietal Maturation and Allow Modelling of Antral Foveolar Hyperplasia
B. C. Jones, G. Benedetti, G. Cala, L. Tullie, I. Simcock, R. Lutman, M. Balys, R. Amiri, J. Sufi, O. Arthurs, S. Eaton, G. Anderson, N. Elvassore, V. S. Li, K. D. Jones, , P. De Coppi
The paper develops multi-regional gastric assembloids from patient-derived organoids to model parietal cell maturation and antral foveolar hyperplasia in genetic disorders.
bioRxiv · Jul 8, 2024 · PreprintCell Biology