Author

T. Xenakis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Bioengineering· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

F. Michielin· 2 shared J. Deprest· 2 shared P. De Coppi· 2 shared S. Eaton· 2 shared A. A. Straatman-Iwanowska· 1 shared A. Alhendi· 1 shared A. Dos Santos Dias· 1 shared A. Khabbush· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCell Biology

F. Michielin

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Single cell-guided prenatal derivation of primary epithelial organoids from the human amniotic and tracheal fluids.

M. F. M. Gerli, G. Cala, M. A. Beesley, B. Sina, L. Tullie, F. Panariello, F. Michielin, K. Y. Sun, J. R. Davidson, F. M. Russo, B. C. Jones, D. Lee, S. Savvidis, T. Xenakis, I. C. Simcock, , P. De Coppi

The paper derives epithelial organoids from human amniotic and tracheal fluids to model congenital malformations and predict disease outcomes.

Nature Medicine · Mar 4, 2024Peer-reviewedCell Biology

Prenatal VEGF Nano-Delivery Reverses Congenital Diaphragmatic Hernia-Associated Pulmonary Abnormalities

S. Loukogeorgakis, F. Michielin, S. Shibuya, N. Al-Juffali, J. Jimenez, J. Allen-Hyttinen, P. Eastwood, A. Alhendi, J. Davidson, E. Naldi, P. Maghsoudlou, A. Tedeschi, S. Khalaf, A. Khabbush, M. Plate, , P. De Coppi

This paper investigates VEGF supplementation as a treatment for congenital diaphragmatic hernia (CDH)-associated lung abnormalities using an ex vivo model and nanoparticle-based delivery in vivo.

bioRxiv · Feb 20, 2024Bioengineering

Short-term Rho-associated kinase inhibitor treatment accelerates primary keratinocyte growth while preserving stem cell characteristics

V. Jayarajan, G. T. Hall, T. Xenakis, N. Bulstrode, D. Moulding, S. Castellano, W.-L. Di

Short-term ROCKi treatment accelerates keratinocyte growth without compromising stem cell characteristics, suggesting a safe method for clinical applications.

bioRxiv · Jun 28, 2022Cell Biology

Integrated transcriptomics and metabolomics reveal signatures of lipid metabolism dysregulation in HepaRG liver cells exposed to PCB 126

R. Mesnage, M. Biserni, S. Balu, C. Frainay, N. Poupin, F. Jourdan, E. Wozniak, T. Xenakis, C. A. Mein, M. A. Antoniou

This study uses transcriptomics and metabolomics to show PCB 126 exposure disrupts lipid metabolism in HepaRG cells, causing oxidative stress and altered metabolite levels.

bioRxiv · Feb 3, 2018Pharmacology & Toxicology