Imaging of existing and newly translated proteins elucidates mechanisms of sarcomere turnover
G. Douvdevany, I. Erlich, L. Haimovich-Caspi, T. Mashiah, M. Prondzynski, M. R. Pricolo, J. Alegre-Cebollada, W. A. Linke, L. Carrier, I. Kehat
The paper uses imaging to show that sarcomere proteins are replaced by newly translated ones, disproving the existing protein pool model and revealing a unidirectional replacement mechanism.
bioRxiv · Aug 31, 2023Cell Biology