Structure-guided stabilization improves the ability of the HIV-1 gp41 hydrophobic pocket to elicit neutralizing antibodies
T. U. J. Bruun, S. Tang, G. Erwin, L. Deis, D. Fernandez, P. S. Kim
This study shows that stabilizing the HIV-1 gp41 hydrophobic pocket with a modified peptide improves antibody response and neutralizing activity against HIV-1.
bioRxiv · Dec 22, 2022Biochemistry