Author

G. Fallata

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Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

D. M. Wall· 1 shared D. Xu· 1 shared L. M. Meikle· 1 shared M. J. Ormsby· 1 shared X. Li· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperMicrobiology

D. M. Wall

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1 paper

Recent·Most cited

Inhibition of proline tyrosine kinase 2 (Pyk2) phosphorylation during adherent-invasive Escherichia coli infection inhibits intra-macrophage replication and inflammatory cytokine release

X. Li, M. J. Ormsby, G. Fallata, L. M. Meikle, D. Xu, D. M. Wall

This study shows that inhibiting Pyk2 reduces AIEC replication in macrophages and inflammatory cytokine release, suggesting a potential therapeutic target for Crohn's Disease.

bioRxiv · Nov 14, 2022 · PreprintMicrobiology