Rapid and dynamic nucleic acid hybridization enables enzymatic oligonucleotide synthesis by cyclic reversible termination
K. Hoff, M. Halpain, G. Garbagnati, J. Edwards, W. Zhou
This paper demonstrates an enzymatic method for synthesizing oligonucleotides using cyclic reversible termination, achieving high efficiency and eliminating hazardous chemicals.
bioRxiv · Apr 15, 2019 · PreprintSynthetic Biology