Author

G. Larocque

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 4 Organism:human· 3 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1

Frequent Co-Authors

S. J. Royle· 5 shared N. I. Clarke· 3 shared P. J. La-Borde· 2 shared A. M. Roseman· 1 shared B. J. Wilson· 1 shared C. J. Smith· 1 shared C. Kuey· 1 shared C. Küey· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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5 shared papersCell Biology

S. J. Royle

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Recruitment of clathrin to intracellular membranes is sufficient for vesicle formation

C. Küey, M. Sittewelle, G. Larocque, M. Hernandez-Gonzalez, S. J. Royle

This study shows that clathrin recruitment alone is sufficient for forming intracellular clathrin-coated vesicles, bypassing the need for accessory proteins.

bioRxiv · Mar 21, 2022Cell Biology

Multi-modal adaptor-clathrin contacts drive coated vesicleassembly

S. M. Smith, G. Larocque, K. M. Wood, K. L. Morris, A. M. Roseman, R. B. Sessions, S. J. Royle, C. J. Smith

This study identifies multi-modal adaptor-clathrin interactions essential for coated vesicle assembly, revealing two critical binding sites on AP2's β2 subunit.

bioRxiv · May 22, 2021Biochemistry

Intracellular nanovesicles mediate integrin trafficking during cell migration

G. Larocque, P. J. La-Borde, B. J. Wilson, N. I. Clarke, D. J. Moore, P. T. Caswell, S. J. Royle

This study identifies intracellular nanovesicles (INVs) as mediators of integrin trafficking during cell migration, showing that TPD52-like proteins regulate this process and affect cell migration and invasion.

bioRxiv · Aug 19, 2020Cell Biology

Tumor Protein D54 defines a new class of intracellular transport vesicle

G. Larocque, P. J. La-Borde, N. I. Clarke, N. J. Carter, S. J. Royle

The paper identifies TPD54 as defining a new class of intracellular transport vesicles called INVs, which have specific cargo, R-SNAREs, and Rab GTPases.

bioRxiv · Aug 12, 2019Cell Biology

Unintended inhibition of protein function using GFP nanobodies in human cells

C. Kuey, G. Larocque, N. I. Clarke, S. J. Royle

The paper demonstrates that GFP nanobodies can inhibit protein function in human cells, limiting their use for knocksideways experiments.

bioRxiv · May 30, 2019Cell Biology