Distinct clonal evolution of B-cells in HIV controllers with neutralizing antibody breadth
D. Cizmeci, G. Lofano, A.-S. Dugast, D. Kim, G. Cavet, N. Nguyen, Y. C. Tan, M. S. Seaman, G. Alter, B. Julg
The paper analyzes B-cell receptor repertoires in HIV controllers to identify clonal evolution and somatic hypermutation associated with neutralizing antibody breadth.
bioRxiv · Sep 2, 2020Immunology