Mucins shed from the laminated layer in cystic echinococcosis are captured by Kupffer cells via the lectin receptor Clec4F
A. A. Barrios, C. Mouhape, L. Schreiber, L. Zhang, J. Nell, M. Suarez-Martins, G. Schlapp, M. N. Meikle, A. P. Mulet, T.-L. Hsu, S.-L. Hsieh, G. Mourglia-Ettlin, C. Gonzalez, M. Crispo, T. F. E. Barth, , A. Diaz
The paper shows that mucins from the laminated layer of E. granulosus are captured by Kupffer cells via Clec4F, highlighting a mechanism for host clearance of parasite-derived materials.
bioRxiv · Oct 6, 2022Immunology