17-Oxime ethers of oxidized ecdysteroid derivatives modulate oxidative stress in human brain endothelial cells and dose-dependently might protect or damage the blood-brain barrier
M. Vagvolgyi, D. Laczko, A. R. Santa-Maria, F. R. Walter, R. Berkecz, M. Deli, G. Toth, A. Hunyadi
The paper synthesizes and evaluates 17-oxime ethers of oxidized ecdysteroids, finding they modulate oxidative stress in BBB cells with dose-dependent protective or damaging effects.
bioRxiv · Aug 11, 2023Pharmacology & Toxicology