Chemerin increases T-cell mediated cytotoxicity of human tumors via modulation of a novel CMKLR1/PTEN/PD-L1 axis
K. Rennier, E. Krug, G. Virdi, W. J. Shin, R. Pachynski
This study shows chemerin enhances T-cell cytotoxicity against tumors by modulating the CMKLR1/PTEN/PD-L1 axis, with effects comparable to PD-L1 inhibition.
bioRxiv · Sep 30, 2019 · PreprintCancer Biology