Cancer BiologybioRxivPreprint
Chemerin increases T-cell mediated cytotoxicity of human tumors via modulation of a novel CMKLR1/PTEN/PD-L1 axis
K. Rennier, E. Krug, G. Virdi…·R. Pachynski
This study shows chemerin enhances T-cell cytotoxicity against tumors by modulating the CMKLR1/PTEN/PD-L1 axis, with effects comparable to PD-L1 inhibition.
DOI 10.1101/787697