A Humanized Animal Model Predicts Clonal Evolution and Therapeutic Vulnerabilities in Myeloproliferative Neoplasms
H. Celik, E. Krug, C. R. Zhang, W. Han, N. Issa, W. K. Koh, H. Bjeije, O. Kukhar, M. Allen, T. Li, D. A. Fisher, J. Fowles, T. N. Wong, M. C. Stubbs, H. K. Koblish, , G. A. Challen
This paper introduces a humanized animal model using patient-derived xenografts to study myeloproliferative neoplasms and identify therapeutic vulnerabilities.
bioRxiv · Nov 12, 2020Cancer Biology