Hypoxia impedes differentiation of cranial neural crest cells into derivatives relevant for craniofacial development
Theresa Schmid, Gabriele Rodrian, Elke Bachmann, Alexander Kohler, Michael Wegner, Lina Gölz, Matthias Weider
The paper shows hypoxia impairs differentiation of cranial neural crest cells into chondrocytes, osteoblasts, and smooth muscle cells, linking it to orofacial cleft risk.
Open Biology · Jul 1, 2025Peer-reviewedGenomics