Author

Alexander Kohler

German Center for Infection Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Abdelhakim BoudriouaiD· 1 shared Antje FliegeriD· 1 shared Antti PosoiD· 1 shared Arun Naini· 1 shared Claudio PiselliiD· 1 shared Elke Bachmann· 1 shared Gabriele Rodrian· 1 shared Gert BangeiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMicrobiology

Abdelhakim BoudriouaORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Hypoxia impedes differentiation of cranial neural crest cells into derivatives relevant for craniofacial development

Theresa Schmid, Gabriele Rodrian, Elke Bachmann, Alexander Kohler, Michael Wegner, Lina Gölz, Matthias Weider

The paper shows hypoxia impairs differentiation of cranial neural crest cells into chondrocytes, osteoblasts, and smooth muscle cells, linking it to orofacial cleft risk.

Open Biology · Jul 1, 2025Peer-reviewedGenomics

Discovery of a synthetic small molecule targeting the central regulator of Salmonella pathogenicity

Abdelhakim Boudrioua, Joe D. Joiner, Iwan Grin, Thales Kronenberger, Vadim S. Korotkov, Wieland Steinchen, Alexander Kohler, Sophie Schminke, Julia-Christina Schulte, Michael Pietsch, Arun Naini, Simon Kalverkamp, Sven‐Kevin Hotop, Travis Coyle, Claudio Piselli, , Samuel Wagner

The paper identifies a synthetic small molecule, C26, that inhibits HilD, a key regulator of Salmonella secretion systems, thereby preventing bacterial invasion of host cells.

Science Advances · Apr 11, 2025Peer-reviewedMicrobiology